Recurrent Cancer This tumor is seldom controlled if it recurs after surgery and radiation therapy , although one-third of patients respond to cisplatin . Phase I and II clinical studies should be considered. Craniopharngioma These benign tumors arise in the central portion of the brain and produce problems primarily because of their location. Since they are benign, metastasis is unknown. Standard Treatment Surgery is the treatment of choice and produces a high rate of control in most patients. For recurrent unresectable tumors, radiotherapy is recommended. There is no reported role for chemotherapy . Ten-Year Survival About 80 percent Intracranial Germ Cell Tumor Germ cell brain tumors--there are a number of sub-types—usually arise in the central portion of the brain. Under the microscope, they resemble more common germ cell tumors of the testis and ovary. The prognosis relates to the cell type and is especially favorable in patients with germinoma.